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Solutions

CAR-T Drug Clinical Trials - Laboratory Solutions


Due to the complexity of tumor biology, tumor drug development is full of challenges. Compared with other diseases, Hematological malignancies require multi-omics platforms (M: morphology, I: immunology, C: cytogenetics, M: molecular biology, etc.) to provide necessary information for disease diagnosis, treatment, prognosis, etc., and rely on the services provided by the central laboratory.


KingMyLab has established a sound MICM and other multi-omics platforms, which can fully support the research of biomarkers related to Hematological malignancies drug development. At present, we have helped more than 300 clinical research projects of Hematological malignancies , involving small molecules, monoclonal antibody/double antibody and other macromolecules, CAR-T (chimeric antigen receptor T cell) and other therapies, covering diseases such as leukemia, lymphoma and multiple myeloma. 

Pharmacokinetics (PK) Study
Pharmacokinetics (PK) Study


Servies CAR Cell Count, CAR Gene Copy Number, etc.

Platforms: Flow Cytometry, qPCR, etc.

Pharmacodynamics (PD) Study
Pharmacodynamics (PD) Study


Servies: Peripheral Blood or Bone Marrow Target Antigen Positive Cells, Tumor Target Antigen Expression, Peripheral Blood Soluble Target Antigen Level, Antigen-Specific Immune Response, etc.

Platforms: Flow, IHC, LBA, etc.


Safety Testing
Safety Testing


Servies: Cytokines and Inflammation-related Markers, Immunogenicity, Replicating lentivirus (RCL) or Replicating Retrovirus (RCR), etc.

Platforms: LBA, Olink, Flow, qPCR, etc.



Efficacy Evaluation
Efficacy Evaluation


ServiesBlood Smear, Bone Marrow Smear, Histopathology; MRD; ctDNA; Blood and urine Tests, etc.

Platforms: FISH, qPCR, NGS, Flow, IHC, etc


Biomarker Exploration
Biomarker Exploration

Servies Markers Related to Immune Cell Function; Immune-related Factors; CAR-T and Immune Cell Typing; Lymphohematopoietic System Tumor Type; Targeting and Pathway-related Markers,etc.

Platforms: LBA, Olink, IHC/mIHC, RNAseq, NGS, etc.